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Recent research further identifies the perioperative period as a golden window for probiotic interventionadministration of Clostridium butyricum CBM588 before/after colon resection shortens time to first flatus by 30% and increases circulating T-cell counts, advancing its role from adjuvant therapy to a core mediator of gut restoration-immune activation-recurrence suppression tumor ecological regulation (Yang et al., 2025)

London: Elsevier

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Methodologically, 3-nitrotyrosine is a useful but not fully specific footprint (requires LC-MS validation and protein-level mapping) and boronate-based probes detect ONOOH and H 2 O 2 unless kinetic discrimination and scavenger controls are used (Benhar et al