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Chronic obstructive pulmonary disease classification, phenotypes and risk assessment

Alcohol 27 , 173177 (2002)

The small effect of cytosine methylation on DNA thermodynamic properties let one to believe that a change of DNA physical properties by themselves, i.e., not ones mediated by the nucleosome and transcription factors, do not need to be considered for a role in epigenetics

(See also 14 for another systematic review with a smaller number of included studies.) Thus, based on the previous literature, subjective and objective sleep quality may exhibit a small but significant correlation at best, mysteriously leaving a major part of variance in sleep quality self-reports unexplained by actual objective indicators of sleep
