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The copper chaperone Ccs1 is important and its requirement is essential for the maturation of SOD1 and its inter-compartmentalization between mitochondria and cytosol (Barchiesi, 2018
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Oxidative stress is closely related to the pathological processes of hearing loss, and riboflavin deficiency may increase lipid peroxidation in cell membranes, accelerating the degeneration of cochlear cells (51)
