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Description
The successful translation of these drugs underscores the critical role of basic research in advancing clinical treatment, highlights the importance of lipid metabolism in various diseases, and reinforces the close link between preclinical research and clinical application, providing valuable insights for future drug development and therapeutic strategy innovations
Veskovic et al
J.ReljaB
Lysine and tryptophan (which is also catabolized via glutaryl-CoA) and by-products of glutaryl-CoA metabolism, such as glutaric acid, 3-hydroxyglutaric acid, and glutarylcarnitine, accumulate in the body, primarily in the brain
