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thiamine is necessary for proper nerve conduction, and neurological signs present when thiamine is lacking

Alcohol's depressant effects on the autonomic nervous system may lead to a complete breakdown of physical coordination and the onset of stupor

in women), insufficient dietary intake or dietary inhibitors (tea, calcium), medications (PPIs, NSAIDs), occult blood loss, plant based diets, vitamin C deficiency, strenuous exercise, and life stages like pregnancy or growth spurts

Archives of Gynecology and Obstetrics vol