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Likewise, RNA-sequencing analyses in postmortem human studies have yielded evidence of a downregulation of PPP3CA, which encodes for calcium-dependent calmodulin-stimulated protein phosphatase, in patients with CTE compared to healthy subjects, and these patterns were inversely correlated with phosphorylation of tau at Ser202/Thr205 (Seo et al., 2017)
The Bivalent Genome: Characterization, Structure, and Regulation
It has been shown to enhance antioxidant enzyme activity, including GPX4, SOD, and CAT, reducing oxidative damage and mitigating ferroptosis in MCAO/R Rats (Zhu W
On the edge: Pharmacological evidence for anxiety-related behavior in zebrafish larvae
