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a review of several studies of megadoses (many times above Danish Recommended Daily Allowances) of vitamin supplements, including B vitamins and vitamin C, given to children with ADHD found no significant effects on their symptoms, and two of these studies found elevated liver enzymes in children given a combination of vitamins B3, B5, B6, and C.37 Studies of micronutrient supplements in adults with ADHD are scarcer

Antidepressants and synaptic plasticity Chronic administration of typical antidepressants that block the reuptake and breakdown of monoamines increase synaptic plasticity at several levels including increased birth of new neurons in the adult hippocampus, increased neurotrophic factor expression, and regulation of synapse formation 10,132,133

However, L-carnitine might improve blood sugar control and decrease body weight in people with diabetes when taken along with certain weight loss medications

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