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Intriguingly, these experiments also demonstrated a moderate decrease in NMDAR currents when copper was applied following DTT treatment raising the possibility that copper may oxidize redox modulatory sites when they are in a reduced state, either directly (Aizenman et al., 1990

We found for the first time that diabetic patients with Gilbert syndrome, who have a genetic variant in UGT1A1 and moderately elevated levels of serum bilirubin levels, had a lower prevalence of vascular complications including retinopathy, nephropathy and cardiovascular disease, comparing to the patients without the syndrome, along with reduced markers of oxidative stress and inflammation [1]

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