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2 (9) e0165

Mitochondrial dysfunction leads to the decrease of NAD + level, resulting in lysosomal acidification and impaired autophagy, and induces ferroptosis, involving the accumulation of iron in lysosomes and lipid peroxidation

HCC827 cells were cultured in RPMI1640 supplemented with 5% FBS and 1 M gefitinib, with or without hHGF or dimeric macrocycle
