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doi: 10.1080/07315724.2006.10719518

LiFWellingMCJohnsonJACoughlinCMulqueenJJakubovskiEet al

The treatment dose is calculated based on the patient's weight, and the treatment is administered weekly once for a minimum period of 10 weeks

Ratios of classical monocytes (CD14-/CD16-), which are more responsible for phagocytosis and initiation/priming of the immune system [254], are higher in patients with ALS and pre-symptomatic SOD1 carriers as compared with healthy controls, but function at a decreased efficacy and invade the CNS, though the difference between the roles of monocytes in the CNS versus systemic circulation are still unknown [255]
