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WT1 has been shown to bind to the IGF-1R promoter and to suppress activity (Werner et al, 1995)

Analytical testing confirms above 99.8 percent purity assay content of 10.49 mg RT identification 1.000 spectrum 999 endotoxin detected but below 0.01 EU per mg and no detectable heavy metals or microbial contamination

For instance, R607A and K610A had reciprocal effects on B-cell and epithelial cell fusion, while V592A and R597A impaired only B-cell fusion [128], and the E595A mutation was particularly notable, enhancing B-cell fusion beyond wild-type levels and revealing a direct gp42-gH interaction in the absence of gL [129]

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