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This suggests that sleep restriction used in clinical practice to treat insomnia can increased SWA and subjective sleep quality in individuals with insomnia, especially those with deficits in SWA as shown in the SSDD and NSDD subtypes
Current approaches include: Continuous Use Approach: Based on clinical trials that used continuous daily administration for 12-24 weeks without scheduled breaks
If any patient experienced a DLT in any given TC, the cohort was to be extended to six patients
Kim Y, Lee J O, Lee J M, et al
