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Clozapine, featured by its enduring immunosuppressive effects and anti-inflammatory properties that alleviate microglial activation, is associated with its adverse effect of agranulocytosis, which is also correlated with its anti-inflammatory action and abatement of oxidative stress damage

PEDF is only highly expressed in undifferentiated human retinal cells, like Y79 retinoblastoma cells, but is either absent or down-regulated in their differentiated counterparts

10.1080/10623320490482619 Summary Keywords diabetes, endothelial cells, EndMT, AMPK, mTORC1, endothelial dysfunctions Citation Srivastava SP, Kopasz-Gemmen O, Thurman A, Rajendran BK, Selvam MM, Kumar S, Srivastava R, Suresh MX, Kumari R, Goodwin JE and Inoki K (2025) The molecular determinants regulating redox signaling in diabetic endothelial cells