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how to give yourself a b12 injection in the buttocks perform intramuscular (IM) injections Buttock Injection Explained: Proper Technique
Description
The anti-catabolic effects become particularly valuable during the caloric deficit created by Tirzepatide therapy

Not sure if this is mostly from change in diet or from the injections on their own, but it seems to be helping so far

You also take this vitamin in combination with other B vitamins, such as B1 and so on
M., Wei X., et al