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Description
Effect of oral semaglutide compared with placebo and subcutaneous semaglutide on glycemic control in patients with type 2 diabetes: a randomized clinical trial
NF- B, nuclear factor-kappa B
Glutathione (GSH) GSH, a naturally occurring antioxidant, plays a vital role in protecting cells from oxidative stress-induced damage, regulating DNA expression, detoxifying reactive metabolites, providing cysteine reservoirs, modulating apoptosis and antigen-presenting cell functions [92]
Furthermore, elucidating the interplay between GSH and critical molecular pathways, including mitochondrial function and lipid metabolism, could provide valuable mechanistic insights and help identify more biomarkers predictive of treatment response