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As summarized by Njalsson and Norgren (2005) and Ristoff and Larsson (2007), of the six enzymes in the -glutamyl cycle, diseases have been associated with defects in five of the enzymes, namely -glutamylcysteine ligase, glutathione synthetase, -glutamyl transpeptidase, dipeptidase, and 5-oxoprolinase
(2018) Tissue healing mechanisms Animal Current Pharmaceutical Design Gwyer et al

ISSN 0027-8424, 1091-6490

L., Su Y., et al