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Such discouraging findings have prompted research efforts directed at the development of small molecules configured to penetrate the blood-brain-barrier (BBB) and stimulate brain neurotrophins
Doing so can increase the risk of serious side effectsfor example, fat-soluble vitamins (such as vitamin A, vitamin D, vitamin E, and vitamin K) can accumulate in the body over time, reaching toxic levels
Combinatorial temporal patterning in progenitors expands neural diversity
