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10.2174/1871530314666141111103217 161 ValenteE.ScottJ

The narrative format was selected to accommodate heterogeneous evidence spanning preclinical mechanisms, clinical trials, and translational barriers where systematic synthesis would be inappropriate

A comprehensive literature search was conducted across peer-reviewed journals, textbooks, and electronic databasesincluding PubMed, Scopus, Web of Science, ScienceDirect, and Google Scholarto collate relevant data