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The switching mechanism of the mitochondrial ADP/ATP carrier explored by free-energy landscapes

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J Control Release 321:122 Andary J, El Ballouz H, Abou-Khalil R (2025) Lebanese medicinal plants with ophthalmic properties

While the largest percentage of intracellular iron is tightly bound to or incorporated into proteins as a cofactor or for storage, small portion of intracellular iron resides in the cytosol and intracellular organelles (e.g., lysosomes) and constitutes a redox-active liable iron pool, which regulates programmed cell death including ferroptosis 42