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In Figure 3, we delineate the hypothetical mechanism of the GHGHRIGF1 axis, which may be mostly mediated by IGF1, on the regulation of mitochondrial biogenesis, mitophagy, and mitochondrial function based on the results of studies in the recent decades
[DOI] [PubMed] [Google Scholar] 18.Ursin R
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Knockdown studies in CNS endothelium indicated activation of the downstream effector eNOS as the principal mechanism underlying the effects of VEGF-A on the BBB
