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GLS-DON and GLS-ZINC03978829 formed 2-5 hydrogen bonds with the GLS catalytic pocket, while GLS-ZINC32296657 formed 1-2 hydrogen bonds

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PolyP 6 associates with D77, K81, D82 and R208 (3.6 , 3.3 , 2.4 and 4.7 ), while ADP forms interaction of ions with residues K81, D82, K103 and R133 (2.9 , 2.8 , 2.9 and 3.0 ) (Fig

Nrf2 as an activator of antioxidant enzymes represents also a promising therapeutic target for retinal ischemia
