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Oxidative stress: Normal pregnancy versus preeclampsia

ROS can induce autophagy through several mechanisms, including direct activation of AMP-activated protein kinase or inhibition of the mammalian target of rapamycin [163, 164]

Nonenzymatic production of endogenous aldehydes One source of endogenous aldehydes is that generated by the non-enzymatic oxidation of lipids and carbohydrates by the superoxide anion radical ( O 2 ) and other reactive oxygen species (ROS)
