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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

However, in scurvy, vitamin C is retained by the brain for neuronal function, and eventual death from the disease is more likely due to lack of vitamin C for collagen synthesis (44)

BMJ 348:f7656 Scholz J, Finnerup NB, Attal N, Aziz Q, Baron R, Bennett MI, Benoliel R, Cohen M, Cruccu G, Davis KD, Evers S, First M, Giamberardino MA, Hansson P, Kaasa S, Korwisi B, Kosek E, Lavandhomme P, Nicholas M, Nurmikko T, Perrot S, Raja SN, Rice ASC, Rowbotham MC, Schug S, Simpson DM, Smith BH, Svensson P, Vlaeyen JWS, Wang SJ, Barke A, Rief W, Treede RD (2019) The IASP classification of chronic pain for ICD-11: chronic neuropathic pain

It is also a powerful antioxidant protecting not just the liver but also the body against oxidative damage