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doi: 10.1021/bi0015459

Magoffin DA, Weitsman SR: Insulin-like growth factor-I regulation of luteinizing hormone (LH) receptor messenger ribonucleic acid expression and LH-stimulated signal transduction in rat ovarian theca-interstitial cells

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In a high-salt-induced hypertensive mouse model, silybin lowers blood pressure and improves vascular relaxation response to acetylcholine through this pathway ( Beyond its impact on hypertension, silybin also exhibits a protective effect on heart failure after myocardial infarction
