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Furthermore, nude mice injected with NSCLC cells overexpressing miR-486 showed no detectable tumors and decreased IGF-1 level, while control mice formed xenograft tumors
Whether the inotropic effect of acute LCAC exposure is positive or negative appears to depend on the exogenous LCAC concentration and treatment duration, the tissue preparation, and the species used in the study

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Clinical study A total of 14 participants were enrolled in this study at the First Affiliated Hospital of Hainan Medical University, comprising 7 DKD patients and 7 healthy controls
