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The arc from an encouraging 12-week readout to a null 24-week pivotal result is a textbook example of that shrinkage, and it is a pattern seen across the metabolic-drug field, not a quirk of this peptide

Endocrinology 148 (10), 46584666

Notably, the lipolytic activity exhibited by AOD 9604 peptide appears analogous to that of growth hormone (hGH), implying a potential shared mechanism wherein both agents exhibit the capacity to upregulate suppressed lipolytic receptor levels in obese mice relative to their lean counterparts

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