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Description
Lycopene from Tomato extract provides powerful UV protection by neutralizing free radicals generated by UV radiation, preventing skin cell damage

Additionally, 4-Octyl itaconate (4OI) suppresses endothelial ferroptosis by activating the Kelch-like ECH-associated protein 1 (Keap1)/Nrf2/GPX4 signaling pathway [89]

Structural tissue-level changes develop over 612 weeks

The ischemic core, the region directly deprived of blood flow, suffers irreversible damage within minutes
