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Description
Coenzyme Q10 (left side of the graph) modulates energy metabolism within mitochondrion, thus leading to the improvement of the energy metabolism of this organelle (first from the left red arrow)

Nonetheless, to date the only FDA- and EMA-approved NRF2 activator for the treatment of relapsing-remitting MS and psoriasis is DMF, and its therapeutic potential in ALS patients in terms of efficacy, safety and tolerability, is now being evaluated in a phase-II clinical trial [313]

Inactivation can be further distinguished into -static substances which only inhibit further growth or -cidal substances which kill the organism (Mcdonnell and Russell, 1999)

Fujita I, et al