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The important values from the nomogram plotting are points on the probable toxicity line, which include an APAP level of 200 g/mL at 4 hours and 25 g/mL at 16 hours after acute ingestion

All these factors disrupt the autophagy machinery, leading to a buildup of protein aggregates and contributing to neuronal toxicity and cell death observed in neurodegenerative conditions ( Nixon et al

26 FridmanJ
[DOI] [PMC free article] [PubMed] [Google Scholar] 252.Tsen KT, TSW, Chang CL, Hung CF, Wu TC, Kiang JG
