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Recent studies demonstrated that NINJ1 deficiency failed to confer protection against ferroptotic cell death induced by RSL3 and ML162, GPX4 inhibitors, in RAW 264.7 cells and murine embryonic fibroblasts (MEFs) [33, 34]

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A: Skin cell turnover occurs approximately every 28 days, meaning visible improvement in pigmentation requires at least one full cycle

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