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Activating transcription factor 4 mediates heat shock protein family A (Hsp70) member 5 expression, which in turn binds to GPX4 resulting in increased GPX4 protein stability with unclear mechanism in pancreatic ductal adenocarcinoma cells [33]
Additionally, the epididymal white adipose tissue, one of the major triglyceride storage tissues, was found not to be impacted by the loss of Gclc and reduced triglycerides in the Gclc L-KO mice (Fig
A 2016 meta-analysis showed that a low-calorie diet combined with carnitine supplementation promotes the oxidation of fat, spares muscle mass, and may also speed the rate of weight loss
It is noteworthy that different strains of probiotics and types of prebiotics may exert their effects through distinct mechanisms
