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Description
Subcutaneous injection delivers the compound into the interstitial space, from which it diffuses into capillaries and enters systemic circulation without passing through the hepatic portal system first
NR gets more NAD+ and NADP+ than similar doses of NAM, and produces three times more ADPR buildupshowing greater NAD+-consuming activities [5]
When looking at the endogenous NAD + fluxes at the systemic level, most organs do not synthesize NAD + de novo, but can utilize NAM made in the liver 39
Kuwasako K, Hay DL, Nagata S, Murakami M, Kitamura K, Kato J
