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Yes, timing genuinely impacts FOXO4-DRI efficacy

Individual Biology Age, genetics, and baseline epithelial turnover rates affect how quickly renewal and signaling stabilize

Co-transfection of cells with the EAAT3 promoter-driven luciferase reporters, specifically WT-luc, followed by treatment with TNF or co-transfection with P65, led to the activation of luciferase activity with the wild-type EAAT3 promoter (WT-TNF or WT-P65)

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