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No, metformin should generally be continued whilst B12 deficiency is investigated and treated, as it plays an important role in diabetes management

Therapeutic peptides and their Cy7-labeled analogs (Table S1 and Figure S14) were synthesized by CPC Scientic (CA, U.S.A.) via standard Fmoc-based SPPS

When a significant interaction was found, follow-up analyses were performed using two-way or one-way repeated measures ANOVAs with Bonferroni corrections and pair-wise comparisons
