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According to the ASA and AANA Closed Claims Projects, pulmonary aspiration of gastric contents is one of the top three serious, sometimes catastrophically adverse events that occur during anesthesia care
It is typically studied in longevity and age-related signaling models, where researchers examine endpoints such as gene expression patterns, cellular stress responses, and telomere-related pathways in preclinical or in vitro systems

In addition, some of these products direct user to follow a potentially dangerous diet
