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Klotho upregulation contributes to the neuroprotection of ligustilide against cerebral ischemic injury in mice

Since intense oxidative stress leads to severe damage of biomolecules, triggering cell death, it is easily understood that GSH metabolism might be upregulated in tumor cells to protect them from damage of oxidant and even promote cancer cell proliferation and metastasis

Mason, B

In a meta-analysis of five casecontrol investigations involving 735 patients with AD and 828 controls, an association between the NQO1 C609T polymorphism and AD in Chinese populations has been demonstrated [9]