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UVVis spectra of flavonoids show two major spectral bands, band I (the cinnamoyl system of the B ring [300400 nm]) and band II (the benzoyl system of ring A [240285 nm]) (Fig

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On one hand, gut dysbiosis facilitates ferroptosis by affecting iron metabolic pathways, like blocking the synthesis and release of hepatic hepcidin and expression of the iron transporter FPN1 to inhibit iron efflux and causing systemic and local iron overload in joints, thus leading to ferroptosis in OA chondrocytes

Efstratiadis A Role of insulin-like growth factors in embryonic and postnatal growth