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This suggests that targeted therapy aimed at Gln metabolism may represent a novel and potentially effective strategy for cancer patients

These observations demonstrate the importance of IRS/PI3K cascade in proper leptin receptor signaling and its anti-obesity effects

[DOI] [PubMed] [Google Scholar] 124.Grimm MO, Grimm HS, Ptzold AJ, Zinser EG, Halonen R, Duering M, Tschape JA, De Strooper B, Mller U, Shen J, Hartmann T

Additionally, in Alzheimer's disease models where neuronal dysfunction was induced by intracerebroventricular injection of A 142, treatment with nicotinamide (NAM) effectively prevented memory deficits (210)