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in the Wang 2023 kidney study it was renoprotective rather than nephrotoxic
That kind of commitment filters out a lot of people before results even show up
Similarly, PrP C , but not PrP Sc , could be labeled by sulfo-NHS-biotin, a cell-impermeable biotinylation reagent, again implying PrP Sc was intracellular [Borchelt 1990]
What This Means Practically You can do everything else right and still introduce the one variable that quietly compromises your research
