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Safety is not an issue because here the requirements are quite strict
Clin Exp Pharmacol Physiol 42(6):632639
Recent evidence has revealed that -lactams are metabolism-dependent bactericidal antibiotics and that reactive metabolic byproducts induced by antibiotics play a crucial role in their bactericidal activity (Belenky et al, 2015)
[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Johnson M.A., Davey A., Park S., Hausman D.B., Poon L.W., Georgia Centenarian S
