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Degenerative changes, such as disc height loss and anterior osteophyte formation, therefore primarily affect the flexibility in flexion/extension and axial rotation 11,28 , which may explain higher correlation of disc degeneration with the range of motion in these motion planes in the present study
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Interestingly, we observed a reduction in the M1-type macrophage marker iNOS in the aorta, along with an increase in the M2-type macrophage marker CD206 following RBM15 knockdown
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