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Down-regulation of 20-HETE synthesis and signaling inhibits renal adenocarcinoma cell proliferation and tumor growth

The rationale involves maintaining optimal healing capacity before injuries occur rather than responding after damage happens

17: Sikiric P, Boban Blagaic A, Krezic I, Zizek H, Kalogjera L, Smoday IM, Vukovic V, Oroz K, Chiddenton HM, Buric S, Antunovic M, Gojkovic S, Strbe S, Skocic M, Sikiric S, Milavic M, Beketic Oreskovic L, Kokot A, Koprivanac A, Dobric I, Sever M, Staresinic M, Batelja Vuletic L, Skrtic A, Seiwerth S

1981), and has a stoichiometric relationship of 1:2 with hydrogen peroxide (Vojinovi et al