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Supplementary information The online version contains supplementary material available at 10.1038/s41467-023-39901-8

Count data was normalized and batch-corrected following the procedure outlined by the ARCHS4 authors 108 : Raw counts were log2(x + 1) transformed and subsequently quantile normalized using the normalize.quantiles function from the preprocessCore R package 113

Nat Rev Immunol (2014) 14(5):32942

This cerebellar damage is associated with increased blood flow to the cerebellum, thalamus, and basal ganglia, as well as elevated systemic and brain levels of ammonia and manganese (Balzano et al., 2018)