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Description
P.El-AgnafO.et al (2009)

Elucidating the role of GCN5L in energy metabolism not only provides deeper insight into its significance in cellular physiological processes but may also facilitate the discovery of new therapeutic targets

To overcome this limitation, research efforts have been devoted to the development of therapeutic agents with biological mechanisms of action that are independent of the oxygen concentration

Therefore, complete simulation of metabolic processes would require inclusion of much more detailed consideration of inhibitory reactions
