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Fragment 176-191 (modified version of AOD9604) is a small piece of human growth hormone (hGH) that is sometimes referred to as the lipolytic fragment. Fragment 176-191 earned this latter name due to the fact that laboratory research has shown it to enhance fat burning, particularly in mice genetically engineered to produce large fat stores

Cho HD, Suh JH, Feng S, Eom T, Kim J, Hyun SM, et al

Aggarwal B, Swisher SG , Hunt K, Jr P, JB, Ajani J, Komaki RR, Molke KL, Lehman J, Bismark M, Walsh GL, Correa AM, Ho L, Liao Z, Lynch P, Rice D, Smythe WR, Stevens C, Vaporciyan AA, Yao J, Roth JA

In addition, A12 combined with docetaxel can arrest cancer cells in the G2-M cell cycle transition and has been proven to negatively regulate cell cycle progression- and cell survival-associated gene expression, thus decreasing the proliferation of tumor cells [104]