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Description
Downstream analysis were performed using the moderate filtering mode, 90% identity and non-merged paralogs to increase overall recall and mitigate the risk of technical artefacts leading to multiple variants of the same gene
In the RT structure, the cyano group at the position of the Michael acceptor enables fast reaction kinetics, the four-membered azetidine ring improves quantum yield and photostability 17 , and the two carboxylic acid groups ensure aqueous solubility and reduce probe binding to hydrophobic cellular structures

While the two former descriptions may seem contradictory, there is a common line of reasoning between the two

TGF produced by IL-10 redirected astrocytes attenuates microglial activation: IL-10 redirects immune activated astrocytes
