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NAD+ is a coenzyme in every cell, vital for converting food to energy via mitochondria and ATP production

Additionally, decreased glutathione peroxidase (GPx-1) activity has been found to increase the risks of stroke and coronary heart disease

RNA 12, 11791187

Stress Reporter Assay of AQ-QI and DEAQ-QI To identify the stress response pathways upon AQ-QI and DEAQ-QI exposure, oxidative stress response (SRXN1-GFP), ER stress response (CHOP-GFP), inflammation response (ICAM1-GFP), and DNA damage response (p21-GFP) pathways were measured with a high-content image-based BAC-GFP stress responses reporter assay ( HepG2-based reporter cells were generated by Bacterial Artificial Chromosome tagging as described previously ( 4 per well in 0.1 mL DMEM, treated subsequently as described above