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Ferroptosis, a type of non-apoptotic cell death, is mediated through free iron-induced lipid peroxidation and is marked by the loss of plasma membrane integrity [67]

A standard workflow typically involves dataset curation, the transformation of peptide sequences or structures into numerical features, model optimization, and rigorous performance validation

-arrestin2 thus functions as a critical adaptor for recruiting the E3 ubiquitin ligase NEDD4 that ubiquitinates agonist-activated 2 ARs [68, 81]

For instance, compounds like kojic acid show promising inhibitory effects but face limitations due to cytotoxicity or allergic reactions