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An update on vitamin B 12 -related gene polymorphisms and B 12 status Genes Nutr 2018;13:2

When symptoms do appear, they are often vague and easily overlooked: Because obvious symptoms are often absent, the condition is frequently discovered accidentally during blood tests (showing elevated liver enzymes) or imaging scans (such as ultrasounds or CT scans) performed for other reasons

39 proteoforms deriving from 25 parent genes were significantly associated with cognitive resilience and frailty, including proteoforms of VGF, SST, CCK and CHGA/B