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The decision, AstraZeneca said, is not related to the safety, efficacy or quality of Nexium IV. The injectable formulation of Nexium, or esomeprazole, is used primarily in emergency and surgical settings to treat bleeding gastric and duodenal ulcers
10.1146/annurev-bioeng-071516-044546 [DOI] [PubMed] [Google Scholar] Yu X., and Long Y.C

Once the transporter is activated drugs are carried out and are no longer able to operate correctly